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Liquid deposition modeling is an energy-efficient, additive manufacturing process for pasty materials. Physical material properties were determined for a water-based paste consisting of the binder carboxymethyl cellulose and wood flour. A continuously operating dual screw extruder was developed, which was used to manufacture a table frame with a height of 18 cm.
Introduction: In the spring of 2020, coronavirus disease 2019 posed a substantial challenge for countries and their healthcare systems. In Germany, over 70% of all cancer patients are treated in an outpatient setting, so gynecologic oncology practices are the guarantors of optimal patient care. We developed a survey to evaluate the management of gynecologic oncology patients.
Methods: The survey consisted of 38 questions and was sent to the members of the Berufsverband Niedergelassener Gynäkologischer Onkologen in Deutschland e.V. (BNGO), a professional association of gynecologic oncologists in the outpatient sector in Germany.
Results: The survey was completed by 54 out of 133 (41%) gynecologic oncologists from 14 out of 15 (93%) federal states where the BNGO is represented. Facing the pandemic, popular measures were mask requirements (100%), restriction of access to practices (94%), increased number of disinfectant dispensers (85%), installment of panes of acrylic glass (76%), or spatial alterations (67%). For most patients the pandemic had no influence on prioritization of therapies (82%) or prescribed systemic treatments (87%). Despite an increase in perceived psychological burden among the staff (72%), 85% (45/54) of the practices were not offered any additional psychological support.
Discussion and Conclusion: As most cancer patients in Germany are treated in an outpatient setting, a suitable reaction of oncology centers to the new circumstances was crucial to secure optimal treatment and patient care. Nevertheless, the low prioritization of mental health or distress of healthcare workers poses a serious threat to the maintenance of optimal medical care in further waves of the pandemic.
Foods consumed by living organisms contain antioxidants of different antioxidant capacities. In a mixture of antioxidants, the resultant antioxidant potential can be different from the mathematical sum of antioxidant activities exerted by individual components. The possible interactions include synergism, antagonism, and additivity between the bioactive compounds. The study was focused on the synergistic, antagonistic, and additive interactions of bioactive components on antioxidant activity in a ternary mixture of green tea (Camellia sinensis) with the added bee honey and Citrus limonum extract. The resultant antioxidant activity was assessed in terms of total phenolic content (TPC), total flavonoid content (TFC), and Trolox equivalent antioxidant capacity (TEAC). Green tea brew held at each temperature with bee honey added and bee honey with Citrus limonum extract added were analyzed for the TPC, TFC, and TEAC. The observed values of TPC, TFC, and TEAC of the binary and ternary mixtures were compared with the expected values or the mathematical sum of each TPC, TFC, and TEAC of individual ingredients. The TPC and TEAC of each sample demonstrated synergism where the effect was antagonistic on TFC. Each sample demonstrated a significant difference (p < 0.05) in all TPC, TFC, and TEAC. The impact of the temperature of green tea brew at which the additives were added, particularly room (29 °C) and chilling temperatures (7 °C), was addressed considering the effect of additive and temperature collectively on the resultant antioxidant activity.
Hintergrund: Die COVID-19(„coronavirus disease 2019“)-Pandemie hat die Ad-hoc-Digitalisierung an Hochschulen vorangetrieben. Zugleich stand die digitale Hochschullehre vor der Herausforderung der Ausgestaltung der Lehre im Zusammenhang mit den vorbestehenden Ressourcen, der digitalen und didaktischen Kompetenzen sowie der zur Verfügung stehenden technischen Infrastruktur.
Ziel der Arbeit/Fragestellung: Das Ziel der Umfrage war die Einschätzung der digitalen Lehre, die die Präsenzlehre infolge der COVID-19-Pandemie zum großen Teil bzw. gänzlich ersetzt hat, aus der Perspektive der Lehrenden in Public Health, Medizin und Pflege.
Material und Methode: Die Querschnitterhebung fand online von Juni bis August 2020 statt und die Daten wurden über www.soscisurvey.de erhoben. Die schriftliche Befragung wurde unter Mitgliedern der Deutschen Gesellschaft für Public Health (DGPH) und des Ausschusses Digitalisierung der Gesellschaft für medizinische Ausbildung (GMA) und der Sektionen Bildung und Beratung der Deutschen Gesellschaft für Pflegewissenschaft (DGP) sowie der Arbeitsgruppe Lehre der Deutschen Gesellschaft für Medizinische Soziologie (DGMS) durchgeführt (n = 100).
Ergebnisse: Bei der Nutzung der digitalen Technologien in den Veranstaltungen rangieren auf der obersten Stelle Präsentationstools, gefolgt von Lernmanagementsystemen, Videoangeboten sowie digitalen Texten. Die Teilnehmenden geben hinsichtlich der Nutzung unterschiedliche (Konferenz‑)Tools an. Das Erstellen von Lehrvideos bejahen 53 % der Befragten, Abstimmungstools) werden bis 50 % als unbekannt genannt. Als Herausforderungen werden digitale Infrastruktur der Hochschulen, fehlende didaktische Beratung/Unterstützung sowie rechtliche Fragen (Nutzungsrechte, Datenschutz) angegeben.
Schlussfolgerung: Neue Technologie werden vorwiegend für Wissenserwerb, Wissensvermittlung genutzt, selten zur Aktivierung von Studierenden und zur Gestaltung kollaborativer Lehr- und Lernarrangements sowie Neugestaltung von Lernaufgaben und Lernprozessen (individualisiertes Lernen). Welche der aktuell erprobten digitalen Lehr- und Lernformate zukünftig in der Hochschullehre zunehmend eingesetzt werden, hängt von vielen Faktoren ab, u. a. von digitaler Kompetenz sowie der Bereitschaft der Lehrenden und Lernenden die digitale Lernkultur mitzugestalten.
The removal of bacterial infections within the root canal system is still a challenge. Therefore, the cleansing effect of established and new irrigation-protocols (IP) containing silver diamine fluoride (SDF) 3.8% on the whole root canal system was analyzed using quantitative PCR (qPCR) and 4′,6-diamidino-phenylindole-(DAPI)-staining. Extracted human premolars were instrumented up to F2 (ProTaper Gold) under NaCl 0.9% irrigation and incubated with Enterococcus faecalis for 42 days. Subsequently, different ultrasonically agitated IP were applied to the roots: control (no irrigation), 1. NaOCl 3%, EDTA 20%, CHX 2%, 2. NaOCl 3%, EDTA 20%, 3. NaOCl 3%, EDTA 20%, SDF 3.8%, 4. SDF 3.8%, and 5. NaCl 0.9%. One half of the root was investigated fluorescent-microscopically with DAPI. The other half was grinded in a cryogenic mill and the bacterial DNA was quantified with qPCR. The qPCR results showed a statistically significant reduction of bacteria after the application of IP 1, 2, and 3 compared to the control group. While IP 4 lead to a bacterial reduction which was not significant, IP 5 showed no reduction. These data corresponded with DAPI staining. With qPCR a new molecular-biological method for the investigation of the complete root canal system was implemented. The novel IP 3 had an equally good cleansing effect as the already established IP.
Routing games over time are widely studied due to various applications, e.g., transportation, road and air traffic control, logistic in production systems, communication networks like the internet, and financial flows. In this article, we present a new competitive packet routing game with edge priorities motivated by traffic and transportation. In this model a set of selfishly acting players travels through the network over time. If the number of players who want to enter an edge at the same time exceeds the inflow capacity of this edge, then edge priorities with respect to the preceding edge are used to resolve these conflicts, which is similar to right-of-way rules in traffic. We analyze the efficiency of pure Nash equilibria, present an efficient algorithm for computing equilibria in symmetric games, and show that it is NP-hard to decide whether a Nash equilibrium exists in an asymmetric game. Furthermore, we address the problem of constructing optimal priorities.
